Understanding Kidney Failure and Its Management
The kidneys perform essential functions that keep the body healthy. They filter waste products and excess fluid from the blood, maintain electrolyte balance, regulate blood pressure and support the production of red blood cells. When kidney function becomes severely reduced, waste and excess fluid can accumulate in the body, resulting in kidney failure.
Kidney failure can develop suddenly, known as acute kidney injury, or gradually as a result of long-standing kidney disease. The appropriate treatment depends on the cause, severity and overall health of the patient. For people seeking Kidney Failure Treatment in Guwahati, early evaluation by a nephrologist is important for determining the appropriate treatment and preventing further complications.
Meet Hayat Hospital’s Nephrology Specialists

Dr. Pranamita Kalita
MBBS, MD (Medicine), DNB (Nephrology)
Consultant
Department of Nephrology

Dr. Amit Roy
MD, DM (Nephrology)
Consultant
Department of Nephrology
Dr. Pranamita Kalita specializes in diagnosing and treating kidney diseases, proteinuria, chronic kidney disease, hypertension-related kidney disorders, and other nephrological conditions. Her patient-focused approach emphasizes early diagnosis and personalized treatment strategies.
Dr. Amit Roy has extensive expertise in managing complex kidney disorders, including proteinuria, kidney failure, diabetic kidney disease, and glomerular diseases. His evidence-based approach helps patients receive comprehensive and effective kidney care.
Together, they provide advanced nephrology services aimed at preserving kidney function and improving patient outcomes.
What Is Kidney Failure?
Kidney failure occurs when the kidneys can no longer perform their functions adequately. Severe loss of kidney function can lead to accumulation of waste products, excess fluid and abnormal levels of minerals such as potassium in the blood.
Kidney failure may be temporary in some cases, particularly when caused by an acute illness and treated promptly. In other patients, progressive chronic kidney disease can eventually lead to end-stage kidney disease, where kidney replacement therapy such as dialysis or transplantation may be required.
What Causes Kidney Failure?
Kidney failure can have several causes. Some of the most common include:
- Long-standing diabetes
- Uncontrolled high blood pressure
- Chronic kidney disease
- Severe kidney infections
- Kidney stones causing prolonged urinary obstruction
- Certain autoimmune kidney diseases
- Severe dehydration
- Serious infections or sepsis
- Certain medicines or toxins
- Congenital or inherited kidney disorders
- Blockage of the urinary tract
In some patients, more than one factor may contribute to declining kidney function. Identifying the underlying cause is an important part of treatment.
Symptoms of Kidney Failure
Early kidney dysfunction may not produce obvious symptoms. As kidney function declines, patients may develop a range of symptoms due to the accumulation of waste and fluid.
Common symptoms may include:
- Swelling of the feet, ankles, face or hands
- Reduced urine output or changes in urination
- Persistent tiredness and weakness
- Nausea or vomiting
- Loss of appetite
- Breathlessness
- Difficulty concentrating
- Sleep disturbances
- Muscle cramps
- Persistent itching
- Changes in skin colour
- High blood pressure
Some patients may have significant kidney impairment without severe symptoms. This is why people at higher risk, particularly those with diabetes or hypertension, should undergo appropriate medical evaluation.
When Should You See a Nephrologist?
A nephrologist specialises in diagnosing and managing kidney disorders. You should consider consulting a nephrologist if blood tests repeatedly show elevated creatinine, if urine tests detect protein or blood, or if kidney function is progressively declining.
People with diabetes, uncontrolled hypertension, recurrent kidney stones, a family history of kidney disease or previously diagnosed CKD may also require regular kidney monitoring.
Early specialist care may help identify potentially treatable causes and slow the progression of chronic kidney disease before kidney failure develops.
How Is Kidney Failure Diagnosed?
Diagnosis begins with a detailed medical history, physical examination and assessment of symptoms. Doctors may perform blood and urine tests to determine how well the kidneys are functioning.
Common investigations include:
- Serum creatinine
- Estimated glomerular filtration rate (eGFR)
- Blood urea nitrogen
- Electrolyte testing
- Urine routine examination
- Urine protein or albumin testing
- Complete blood count
- Blood pressure monitoring
- Ultrasound of the kidneys and urinary tract
Additional imaging, specialised blood tests or kidney biopsy may be recommended in selected patients to determine the underlying cause.
Kidney Failure Treatment in Guwahati: What Are the Treatment Options?
Treatment depends on whether the kidney failure is acute or chronic and on the underlying cause. In acute kidney injury, treating the cause may allow kidney function to improve. This may involve correcting dehydration, treating infections, relieving urinary obstruction or stopping a medicine that is contributing to kidney injury.
For advanced chronic kidney disease, treatment focuses on managing complications and preserving remaining kidney function for as long as possible. This may involve medicines, dietary changes, blood pressure and diabetes management, fluid management and treatment of anaemia or mineral abnormalities.
When kidney function becomes severely impaired, renal replacement therapy may be necessary.
Is Dialysis Required for Kidney Failure?
Dialysis is a treatment that performs some of the functions normally carried out by the kidneys. It can remove waste products and excess fluid from the blood and help manage certain electrolyte abnormalities.
However, not every patient with kidney failure immediately requires dialysis. The decision depends on kidney function, symptoms, fluid status, electrolyte abnormalities, acid-base balance and the patient’s overall clinical condition.
The two major forms of dialysis are haemodialysis and peritoneal dialysis. A nephrologist determines whether and when dialysis is appropriate based on the individual patient’s needs.
FAQ (Frequently Asked Questions)
It depends on the cause. Some cases of acute kidney injury may improve when the underlying problem is treated. Advanced chronic kidney failure is generally not reversible, but appropriate treatment can help manage the condition and its complications.
No. Dialysis is recommended when kidney function is severely reduced and the patient develops clinical or laboratory indications that require kidney replacement therapy. The decision is made by a nephrologist based on the patient’s overall condition.
Kidney function is assessed primarily through blood tests such as serum creatinine and eGFR, along with urine tests and other investigations. Symptoms alone cannot reliably determine the severity of kidney dysfunction.
Patients looking for Kidney Failure Treatment in Guwahati can consult the nephrology team at Hayat Hospital, including Dr. Pranamita Kalita and Dr. Amit Roy, for evaluation, treatment planning and ongoing kidney care.
Yes. Long-standing or poorly controlled diabetes can damage the kidneys and is an important cause of chronic kidney disease. Regular blood sugar control and kidney monitoring are therefore important for people with diabetes.




